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Exchange 2016 performance issues

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We have a Typical issue wherein we have set of 16 Exchange 2016 servers with about 60k users. We have about 8 GC/DC in site,6 GC/DC out of site. Every morning for about 10-20 minutes, the users face performance issues wherin, outlook freezes,owa login is slow, sending emails is slow. When we look at the Exchange and domain controller resource performance (CPU,DISK,MEMORY), it is quite normal and under 50 %. However, the issue still happens. On the DCs, we get a lot of ATQ alerts and get deep LDAP queries for various objects, etc. We are currently unsure what is causing this. Any inputs is very much appreciated.


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